Blood flow-interrupting hyperthermic chemotherapy on established autochthonous mouse sarcoma induced by 3-methylcholanthrene.

Treatment of artificial metastases of methylcholanthrene-induced rat sarcomas by autoimmunization of the autochthonous hosts.

Demonstration of resistance against methylcholanthrene-induced sarcomas in the primary autochthonous host.

by Frehn and Main (13) and by Révész (14) that methylcholanthrene-induced sarcomas, but not spontaneous mammary carcinomas, can induce a state of resistance in isologous mice, i.e., members of the same highly inbred strain in which they have originated. Spontaneous fibrosarcomas in mice did not induce a similar resistance (13). Analogous positive results have been obtained by Baldwin (1) on m...

Experimental radiation therapy and apparent radioresistance of autochthonous tumors subcutaneously induced with 3-methylcholanthrene in mice.

The radiation response of autochthonous tumors induced by s.c. injection of 3-methylcholanthrene in ICR/JCL mice was studied. The tumors were mostly fibrosarcomas and grew with an average volume-doubling time of 2.6 days, independently of the time tumor appearance or dose of the chemical used. The tumors were locally and singly irradiated with 6-MV X-rays through a filter. Autochthonous tumors ...

Experimental Radiation Therapy and Apparent Radioresistance of Autochthonous Tumors Subcutaneously Induced with 3-Methylcholanthrene in Mice1

The radiation response of autochthonous tumors induced by s.c. injection of 3-methylcholanthrene in ICR/JCL mice was studied. The tumors were mostly fibrosarcomas and grew with an average volume-doubling time of 2.6 days, independently of the time of tumor appearance or dose of the chemical used. The tumors were locally and singly irradiated with 6-MV X-rays through a filter. Autochthonous tumo...

Demonstration of host resistance against sarcomas induced by implantation of cellophane films in isologous (syngeneic) recipients.

Whether it is possible to build up host resistance against sarcomas induced by the implantation of cellophane films was studied by pretreating autochthonous and isologous (syngeneic) hosts with heavily irradiated cells of the same tumor. In the ten available autochthonous hosts, whose tumors had been operatively removed, no resist ance could be demonstrated after pretreatment with irradiated ce...